Syphilis

Medically Reviewed

Syphilis is a bacterial STI that progresses through stages and is easily cured with antibiotics if caught early. It can be detected with a blood test from 3 weeks after exposure. Symptoms start with a painless sore, followed by rash and flu-like symptoms if untreated.

Syphilis: Key Facts

Incubation Period
10-90 days (average 21 days)
Test Window
3-4 weeks post-exposure
Results
24-48 hours
Treatment
Penicillin injection
Cure Rate
100% in early stages
Book Syphilis Test – £135

Results within 24 hours • Same-day treatment available

Symptoms of Syphilis

Common Symptoms

  • Primary: Painless sore (chancre) at infection site
  • Secondary: Rash on palms/soles, flu-like symptoms
  • Latent: No symptoms but still infected
  • Tertiary: Serious organ damage (rare with treatment)

Symptoms in Men

  • Painless sore on penis or around anus
  • Body rash including palms and soles
  • Flu-like symptoms
  • Swollen lymph nodes

Symptoms in Women

  • Painless sore on vulva, vagina, or cervix
  • Body rash including palms and soles
  • Patchy hair loss
  • Swollen lymph nodes

How is Syphilis Transmitted?

  • Direct contact with syphilis sore
  • Vaginal, anal, or oral sex
  • From mother to baby during pregnancy

Prevention

  • Use condoms (reduces but doesn't eliminate risk)
  • Regular testing
  • Avoid contact with visible sores
  • Partner notification and treatment

Complications if Untreated

  • Brain and nervous system damage
  • Heart problems
  • Blindness
  • Pregnancy complications
  • All preventable with early treatment

Frequently Asked Questions

Dr Mohammad Bakhtiar
Medically Reviewed

Dr Mohammad Bakhtiar

MD, PhD, LRCP, MSc, DHMSA

Sexual Health

GMC: 4694470Last reviewed: January 2026

All medical content is reviewed by qualified healthcare professionals registered with the General Medical Council (GMC).

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